Drosophila wing development is a paradigm for understanding how spatial information is conveyed by morphogen gradients to coordinate pattern formation and organ growth. Central to this process is ...
The research team has shown that a transcriptional co-activator ANGUSTIFOLIA3 (AN3) forms a signaling gradient along the leaf proximal-to-distal axis to determine cell-proliferation domain. In an ...
Tissue patterning is an important process during embryo formation, which ensures that groups of cells are arranged in an appropriate manner that allows them to function properly. Tissue patterning is ...
Cells producing noise in the Wnt morphogen gradient are sensed by neighboring cells through E-cadherin and then eliminated through the Smad-ROS (reactive oxygen species) axis. Disclaimer: AAAS and ...
In a recent study published in Nature Communications, researchers examinea the effects of temporal morphogen gradient during neural induction (NI) on the formation of brain organoids. Study: Temporal ...
Human neural organoids, derived from pluripotent stem cells, enable the study of the highly regulated process of human brain development in vitro. In vivo, the process is shaped by strict time- and ...
Morphogens are signaling molecules that are vital for cell differentiation. These molecules directly influence cell differentiation, inducing specific cellular responses in relation to their ...
In an article published on September 5th in Biophysical Journal, the team of Associate Professor Kensuke Kawade at the Okazaki Institute for Integrative Bioscience and National Institute for Basic ...